Miracil D: inhibition of deoxyribonucleic acid polymerase-deficient Escherichia coli.
نویسنده
چکیده
Miracil D preferentially inhibited the growth of a deoxyribonucleic acid (DNA) polymerase-deficient Escherichia coli strain. This is taken to indicate that miracil D is capable of altering the DNA of living cells and that it may thereby be a potential mutagen and carcinogen.
منابع مشابه
Use of miracil D to suppress bacterial ribonucleic acid and protein synthesis during bacteriophage MS2 infection.
Under certain culture conditions, Miracil (35 mug/ml) halts the growth of uninfected Escherichia coli. Cellular ribonucleic acid (RNA) synthesis is almost completely suppressed, whereas deoxyribonucleic acid and protein synthesis are inhibited to a lesser extent. When the drug is added to host bacteria prior to infection with bacteriophage MS2, the phage adsorb to the cells, but penetration of ...
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ورودعنوان ژورنال:
- Antimicrobial agents and chemotherapy
دوره 3 4 شماره
صفحات -
تاریخ انتشار 1973